Thrombocytopenia Complicating the Clinical Course of Leptospiral Infection

Mild Clinical Course of Severe Fever with Thrombocytopenia Syndrome Virus Infection in an Elderly Japanese Patient

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious and hemorrhagic disease recently described in China and western Japan. A 71-year-old healthy Japanese woman noticed a tick biting her after harvesting in an orchard and removed it herself. She developed diarrhea, anorexia, and chills eight days later. Because these symptoms continued, she visited a primary care physici...

Seroprevalence of Leptospiral infection in goats of Ahvaz

Time course and clinical relevance of thrombocytopenia in critical illness

Introduction Thrombocytopenia is a common laboratory finding among critically ill patients. Studies have shown that thrombocytopenia is associated with increased morbidity and mortality, however there is limited evidence showing increasing mortality with increasing severity of thrombocytopenia. Several risk factors, such as sepsis and surgery, have been associated with thrombocytopenia. The rel...

CLINICAL TRIALS AND OBSERVATIONS Impact of immune thrombocytopenia on the clinical course of chronic lymphocytic leukemia

The prevalence, clinical characteristics, and prognostic significance of immune thrombocytopenia (IT) in patients with chronic lymphocytic leukemia (CLL) have not been clearly determined. To clarify this, we retrospectively analyzed 1278 consecutive newly diagnosed patients with CLL. Criteria for IT diagnosis included the following: rapid (< 2 weeks) and severe fall (half of the initial level a...

Fournier's gangrene complicating thrombocytopenia treated with steroids.

A 66-year-old man developed sudden perineal discomfort and fever with painful anal, penile, and scrotal oedema during treatment with steroids for severe thrombocytopenia of unclear origin (whether auto immune thrombocytopenia or myelodysplastic syndrome). An anal fi stula was observed and CT scan showed emphysematous gangrene of the perineum and scrotum, with testicles suspended in this emphyse...